Fudan University, China

Weidong Qu, Chang Jiang Scholar Professor of Ministry of Education, People’s Republic of China, Department of Environmental Health, Director of Institutes of Water and Health, School of Public Health, Fudan University ...

...Dr. Qu earned PhD in West China University of Medical Sciences (Chengdu) in 1998, an post-doctoral training in Shanghai Medical University (Environmental Health) and University of North Carolina at Chapel Hill (Reproductive Biology). In 2003, he came back Fudan University as associate professor of environmental health and as a Co-PI conducted 863 Project. He is a PI of the key project for the Eleventh Five Years Plan on National of Scientific Supportive Plan 2005-2010, and Assistant Dean of SPH from 2004-2013, Vise Chair of Departmental of Environmental Health from 2006-2013, and associate Dean for Research, School of Public Health from 2013-2017. In 2017 he led the effort in winning a key project on Food Safety (2017YFC1600200) from Ministry of Science & Technology of People’s Republic of China. Over 50 well established investigators from 12 leading University and institutes in China are involved in the project. Based on multidisciplinary background and training, his studies focused on the effects of water pollution on health especially in cancer and adverse reproductive outcome. Since 2004, his group has been working in Huai River Basin to investigate the factor caused the cancer cluster and to develop the strategy for improving infrastructure sanitation, waste water and rubbish management and drinking water quality, advocated health education and behavior promotion. He insisted in to seek public health issue onsite, to explore causes in the laboratory, and to return onsite for treatment. He has served as consultant to the National Environment and Health Committee and the Committee of National Standards for Environmental Health; He is Deputy Chair of two branches for Chinese Association of Preventive Medicine, Hygienic Toxicology and Environmental Health. Currently he is associated editor in chief of the Chinese Journal of Preventive Medicine.

 

Abstract


Scientific evidence uncovered cancer cluster in Huai River Basin of China

Weidong Qu1, *, Weiwei Zheng 1, Yubin Zhang1,Peng Xue 1, Yuxin Zheng 2, Weimin Ye 3

1 Centers for Water and Health, Key Laboratory of the Public Health Safety, Ministry of Education; Department of Environmental Health, School of Public Health, Fudan University, Shanghai, 200032, China.

2 School of Public Health, Qingdao University, 38 Dengzhou Road, Qingdao, 266021, China

3 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 171 77, Sweden

Water pollution from industrial activity has become a critical issue for public health in China and worldwide. Since the middle 1980s water pollution is gradually increased in the Huai River Basin (HRB) accompanying the development of industrialization, which has wreaked havoc on public health. The digestive tract cancer incidence and mortality rates have soared over the past two decades. Although several epidemiological investigations have suggested that drinking-water pollution may be the most serious factor contributing to cancer mortality in the HRB, there is still lack of evidence to confirm causes of cancer in these communities. The issues of cancer in HRB have been paid much concern by the public, government and, academic community. Since 2005 the Chinese government has endeavored to implement pollution control and to provide safe drinking water in the HRB. The enterprises which caused serious pollution were closed or improved by implementing treatment of polluted water, meanwhile, extracting water from deep wells unpolluted by industrial effluent acts as the strategy for access to “safe drinking water”. Here we report our studies on drinking water contamination and cancer risk and share experiences in the process of conducting project for a period of 15 years. Our studies provide solid evidence that high cancer risk is associated with drinking water pollution in HRB, based on epidemiological investigation and toxicological test. The intervention by directly extracting deep-well water as a safe drinking water in high cancer incidence areas has instead brought about the problem of dental fluorosis in children, owing to high fluoride concentration in deep-well water. There is not high fluoride and arsenic determined in that areas’ surface water and shallow well water, soil, and food. The lessons learned in China teach us that industrial activity without proper safeguards results in serious public health consequences. Top designation with comprehensive and systematic strategy for pollution control, public health intervention, health education and, health promotions needs to be implemented in HRB area in order to solve the difficult health problem by environmental pollution