Eawag/ETH, Switzerland

Prof. Dr. Juliane Hollender is the head of the department Environmental Chemistry at the Swiss Federal Institute of Aquatic Science and Technology (Eawag) as well as adjunct professor at the ETH Zurich.

She holds a PhD in environmental engineering from the Technical University of Berlin and worked for 10 years at the RWTH Aachen in Germany before she moved to Switzerland in 2005. Her research concentrates on the fate of organic micropollutants in the natural and engineered aquatic environment. She is especially interested in biological transformation of contaminants in the environment, bioaccumulation in aquatic organisms as well as non-target analysis using high resolution mass spectrometry to get a more comprehensive picture of the contamination of aquatic systems. She is a member of scientific research groups and committees including the research council of the Swiss National Science Foundation and the NORMAN network.



Emerging analytical tools facilitate linking chemical exposure and effects in aquatic systems

Juliane Hollender1,2,*

1Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dübendorf, Switzerland

2Institute of Biogeochemistry and Pollutant Dynamics, ETH Zürich, 8092 Zürich, Switzerland

In traditional risk assessment effect and exposure of chemicals are studied separatedly and only in the final step the concentrations in the environmental compartment such as water or sediment are compared with effect concentrations determined in laboratory studies. Usually, this is done compound by compound and mixtures are only seldom assessed. In recent years analytical tools have emerged that enable to bring exposure and effect studies much closer together. Especially high-resolution mass spectrometry, capable of high accuracy (< 5 ppm), high mass resolution (0.001 Da), and high sensitivity in the fullscan mode, enables a comprehensive target screening of contaminants in environmental compartments as well as in organisms. Furthermore, unknown toxicants can be identified and elucidation of metabolites helps to describe (de)toxification pathways in the organisms. Several examples from recent laboratory and field studies using mostly invertebrates as test species will be presented.